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For practitioner

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Informing and maintaining a constant dialogue with HCPs is essential for us at Postbiotica.

 

We make our knowledge available by spreading it through meetings, seminars and publications aimed at the sales network that distributes our products and the doctors and nutritionists who prescribe them.

PBTECH®

PBTech® is the innovative technology patented by Postbiotica able to modulate the fermentation process in a natural way.

 

By selecting specific bacterial strains and culture conditions, PBTech® allows to obtain a new class of molecules with a high biological and functional impact, called postbiotics.

Read more about Postbiotica

Products

PostbiotiX Restore

PostbiotiX Motility

PostbiotiX Comfort

PostbiotiX Slowing

PostbiotiX Immuno

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Publications

 

Postbiotics is made up of a team of experienced scientists and researchers, who have developed exceptional expertise in the synthesis and production of postbiotics, reaching important milestones in the field of immunology and microbiota.

Postbiotics – when simplification fails to clarify.
Aguilar-Toalá JE, Arioli S, Behare P, Belzer C, Berni Canani R, Chatel JM, D’Auria E, de Freitas MQ, Elinav E, Esmerino EA, García HS, da Cruz AG, González-Córdova AF, Guglielmetti S, de Toledo Guimarães J, Hernández-Mendoza A, Langella P, Liceaga AM, Magnani M, Martin R, Mohamad Lal MT, Mora D, Moradi M, Morelli L, Mosca F, Nazzaro F, Pimentel TC, Ran C, Ranadheera CS, Rescigno M, Salas A, Sant’Ana AS, Sivieri K, Sokol H, Taverniti V, Vallejo-Cordoba B, Zelenka J, Zhou Z.Nat Rev Gastroenterol Hepatol. 2021 Nov;18(11):825-826. doi: 10.1038/s41575-021-00521-6.

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver.
Bertocchi A, Carloni S, Ravenda PS, Bertalot G, Spadoni I, Lo Cascio A, Gandini S, Lizier M, Braga D, Asnicar F, Segata N, Klaver C, Brescia P, Rossi E, Anselmo A, Guglietta S, Maroli A, Spaggiari P, Tarazona N, Cervantes A, Marsoni S, Lazzari L, Jodice MG, Luise C, Erreni M, Pece S, Di Fiore PP, Viale G, Spinelli A, Pozzi C, Penna G, Rescigno M.Cancer Cell. 2021 May 10;39(5):708-724.e11. doi: 10.1016/j.ccell.2021.03.004. Epub 2021 Apr 1.

The role of gut vascular barrier in experimental alcoholic liver disease and A. muciniphila supplementation.
Grander C, Grabherr F, Spadoni I, Enrich B, Oberhuber G, Rescigno M, Tilg H.Gut Microbes. 2020 Nov 9;12(1):1851986. doi: 10.1080/19490976.2020.1851986.

Analysis of immune, microbiota and metabolome maturation in infants in a clinical trial of Lactobacillus paracasei CBA L74-fermented formula.
Roggero P, Liotto N, Pozzi C, Braga D, Troisi J, Menis C, Giannì ML, Berni Canani R, Paparo L, Nocerino R, Budelli A, Mosca F, Rescigno M.Nat Commun. 2020 Jun 1;11(1):2703. doi: 10.1038/s41467-020-16582-1.

Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth.
Zagato E, Pozzi C, Bertocchi A, Schioppa T, Saccheri F, Guglietta S, Fosso B, Melocchi L, Nizzoli G, Troisi J, Marzano M, Oresta B, Spadoni I, Atarashi K, Carloni S, Arioli S, Fornasa G, Asnicar F, Segata N, Guglielmetti S, Honda K, Pesole G, Vermi W, Penna G, Rescigno M.Nat Microbiol. 2020 Mar;5(3):511-524. doi: 10.1038/s41564-019-0649-5. Epub 2020 Jan 27.

The gut-liver axis in liver disease: Pathophysiological basis for therapy.
Albillos A, de Gottardi A, Rescigno M.J Hepatol. 2020 Mar;72(3):558-577. doi: 10.1016/j.jhep.2019.10.003. Epub 2019 Oct 14.

Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development.
Mouries J, Brescia P, Silvestri A, Spadoni I, Sorribas M, Wiest R, Mileti E, Galbiati M, Invernizzi P, Adorini L, Penna G, Rescigno M.J Hepatol. 2019 Dec;71(6):1216-1228. doi: 10.1016/j.jhep.2019.08.005. Epub 2019 Aug 13.

Can Postbiotics Represent a New Strategy for NEC?
Mosca F, Gianni ML, Rescigno M.Adv Exp Med Biol. 2019;1125:37-45. doi: 10.1007/5584_2018_314.

The microbiota revolution: Excitement and caution.
Rescigno M.Eur J Immunol. 2017 Sep;47(9):1406-1413. doi: 10.1002/eji.201646576. Epub 2017 Jul 31.

A ‘fit’ microbiota to potentiate cancer immunotherapy.
Rescigno M.Genome Med. 2015 Dec 21;7:131. doi: 10.1186/s13073-015-0256-x.

A gut-vascular barrier controls the systemic dissemination of bacteria. 
Spadoni I, Zagato E, Bertocchi A, Paolinelli R, Hot E, Di Sabatino A, Caprioli F, Bottiglieri L, Oldani A, Viale G, Penna G, Dejana E, Rescigno M.2015 Nov 13;350(6262):830-4. doi: 10.1126/science.aad0135.

BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity.
Fransen F, Zagato E, Mazzini E, Fosso B, Manzari C, El Aidy S, Chiavelli A, D’Erchia AM, Sethi MK, Pabst O, Marzano M, Moretti S, Romani L, Penna G, Pesole G, Rescigno M. 2015 Sep 15;43(3):527-40. doi: 10.1016/j.immuni.2015.08.011. Epub 2015 Sep 8.

Dendritic cell functions: Learning from microbial evasion strategies.
Rescigno M. Semin Immunol. 2015 Apr 2. pii: S1044-5323(15)00020-2. doi: 10.1016/j.smim.2015.03.012. [Epub ahead of print]

Intestinal microbiota and its effects on the immune system.
Rescigno M. Cell Microbiol. 2014 Jul;16(7):1004-13. doi: 10.1111/cmi.12301. Epub 2014 May 1.

Lactobacillus paracasei CBA L74 Metabolic Products and Fermented Milk for Infant Formula Have Anti-Inflammatory Activity on Dendritic Cells In Vitro and Protective Effects against Colitis and an Enteric Pathogen In Vivo.
Zagato E, Mileti E, Massimiliano L, Fasano F, Budelli A, Penna G, Rescigno M. PLoS One. 2014 Feb 10;9(2):e87615. doi: 10.1371/journal.pone.0087615. eCollection 2014.

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells.
Mazzini E, Massimiliano L, Penna G, Rescigno M. 2014 Jan 21. pii: S1074-7613(14)00003-X. doi: 10.1016/j.immuni.2013.12.012. [Epub ahead of print]

Richness of human gut microbiome correlates with metabolic markers.
Le Chatelier E, Rescigno M, Brechot C, M’Rini C, Mérieux A, Yamada T. 2013 Aug 29;500(7464):541-6. doi: 10.1038/nature12506.

The impact of probiotics and prebiotics on the immune system.
Klaenhammer TR, Kleerebezem M, Kopp MV, Rescigno M. Nat Rev Immunol. 2012 Oct;12(10):728-34. doi: 10.1038/nri3312.

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model.
Tsilingiri K, Barbosa T, Penna G, Caprioli F, Sonzogni A, Viale G, Rescigno M. 2012 Feb 1.

Enterotypes of the human gut microbiome. 
Arumugam M, Raes J, Pelletier E, Le Paslier D, Yamada T, Mende DR, Fernandes GR,…R, Rescigno M, Sanchez N, Sunagawa S, Torrejon A, Turner K, Vandemeulebrouck G, Varela E, Winogradsky Y, Zeller G, Weissenbach J, Ehrlich SD, Bork P. 2011 May 12;473(7346):174-80. Epub 2011 Apr 20.

Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity.
Saccheri F, Pozzi C, Avogadri F, Barozzi S, Faretta M, Fusi P, Rescigno M. Sci Transl Med. 2010 Aug 11;2(44):44ra57.

Host-bacteria interactions in the intestine: homeostasis to chronic inflammation.
Barbosa T, Rescigno M. Wiley Interdiscip Rev Syst Biol Med. 2010 Jan-Feb;2(1):80-97.

Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: prediction for in vivo efficacy.
Mileti E, Matteoli G, Iliev ID, Rescigno M. PLoS One. 2009 Sep 16;4(9):e7056.

Dendritic cells in intestinal homeostasis and disease.
Rescigno M, Di Sabatino A. J Clin Invest.2009 Sep;119(9):2441-50.

Intestinal immune homeostasis is regulated by the cross-talk between epithelial cells and dendritic cells.
Rimoldi, M., Chieppa, M., Salucci, V., Sonzogni, A., Nespoli, A., Viale, G., Allavena, P., Rescigno, M.
(2005) Nat Immunol. 6:507-14.

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