07 Nov Innovation at the 25th IFSCC congress: postbiotics for healthy skin and microbiota.
The 25th edition of the Ifscc conference, an international event dedicated to cosmetological sciences promoted by the International Federation of Chemical Products Companies, has witnessed two important contributions by our company. Postbiotica, represented by the founder Maria Rescigno, once again affirmed the central role in helping to maintain and / or restore balance in the skin microbiota, strengthen skin defenses, promote barrier function, reduce inflammation and itching, thus protecting the skin from irritating stimuli and aging factors, thanks to “postbiotics”.
The skin, human body’s largest organ, represents an ecosystem comprising about 1.000 species of microorganisms, which form the skin microbiota, an essential component of skin health. Not only are many of these microorganisms harmless, they also provide important functions that the human cells have not evolved. Indeed, by supporting skin barrier function and modulating immune responses, symbiotic microorganisms protect the skin against pathogens, allergens, photoaging, free radicals and pollutants.
The perception of the skin as a finely organized ecosystem, allows understanding the delicate balance between the host and microorganisms. Balance in microbial patterns is a key factor in preserving skin homeostasis. Disruptions of this balance can induce alterations in skin barrier function and the subsequent onset of dermatological disorders (e.g. acne, eczema, psoriasis, atopic dermatitis, photoaging etc.)
The use of living or tyndalized probiotics and symbiotics, or of prebiotics and bacterial lysates, in food and cosmetic industry has been blooming in recent years. However, the production of stable formulations containing living microorganisms still represents a challenge and their application on irritated skin can rise questions about their safety.
Some studies have highlighted that the released metabolites of these bacteria mediate the immunomodulatory effect conferred to the host. It can be therefore postulated that bacteria interact with each other and with skin cells, using a complex network of molecules named “postbiotics”. Postbiotics represent a new class of soluble factors (mainly peptides, fatty acids and biosurfactants) produced by living bacteria.
We propose the use of purified cell-free postbiotics obtained from Lactobacillus paracasei, a bacterial strain known for its beneficial effects on skin, as a safer and more effective alternative to prebiotics, probiotics and lysates to modulate skin immune response, strengthen the skin barrier, rebalance skin homeostasis and definitely improve skin health and appearance.